- Sandwich Shop Restaurants, Pine Island
- Satellite TV Service, Pine Island
- Security Brokers & Dealers, Pine Island
- Senior Citizens Service & Health Organizations, Pine Island
- Sewer Construction Contractors, Pine Island - Sewer Line, Pipe Installation & Repair Services
- Shopping & Shopping Services, Pine Island
- Siding Contractors, Pine Island - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Snow Removal Services, Pine Island - Snow Plow Service
- Snowmobile Repair, Parts, Sales & Service, Pine Island
- Social Services & Welfare, Pine Island
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- Solar Products & Services, Pine Island
- Special Dies Tools Jigs & Fixtures Manufacturers, Pine Island
- Special Interest Schools Or Instruction, Pine Island
- Specialty Stores, Pine Island
- Sporting Goods Stores, Pine Island
- Sports Bars & Lounges, Pine Island
- Stone, Pine Island
- Stone & Rock Quarry, Pine Island - Gravel Pit, Shale, Granite, Limestone, Crushed Rock, etc
- Stoves & Furnace Equipment, Pine Island - Fittings & Repair Parts
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