- Sand Gravel & Aggregate, Melrose
- Sandwich Shop Restaurants, Melrose
- Satellite TV Service, Melrose
- Savings Banks, Melrose
- School - Catholic, Melrose
- School - Christian, Melrose
- Scrap & Waste Machinery, Melrose
- Scrap & Waste Materials, Melrose
- Screen Printing, Melrose
- Secondary Schools, Melrose
- Security Alarm Systems - Home & Business, Melrose
- Security Brokers & Dealers, Melrose
- Security Control Systems & Monitoring, Melrose - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Guard & Patrol Service, Melrose - Bodyguard, Guard Dogs, Etc
- Security Services, Melrose
- Seeds & Bulbs Wholesale & Growers, Melrose
- Septic Tanks & Systems Contractors & Designers, Melrose
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- Sewage Septic Service, Melrose
- Shopping & Shopping Services, Melrose
- Signs, Melrose
- Snow Removal Equipment Repair & Service, Melrose
- Social Services & Welfare, Melrose
- Sod & Sodding Service, Melrose
- Sod Farms, Melrose
- Specialty Animal Services, Melrose
- Specialty Goods Storage, Melrose
- Specialty Stores, Melrose
- Sports & Recreational Services, Melrose
- Sports Bars & Lounges, Melrose
- Stadiums, Arenas, Coliseums & Athletic Fields, Melrose
- Stationery & Office Supplies, Melrose
- Stoves & Furnace Equipment, Melrose - Fittings & Repair Parts
- Submarine Sandwich Restaurants, Melrose
- Surveyor Services, Melrose - Surveying Service
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